Role to Interleukin-17 levels in Urine in UTI Patients

Abstract

In order to determine whether Interleukin-17 levels in urine specimens for patients with urinary tract infections (UTI) caused by E. coli and S. aureus in Iraqi patients are related, a case control study was proposed. Around 200 clinical specimens of midstream urine were collected from Iraqi patients suffering from UTIs from Al-Salam teaching hospital. An extra only 10 of mid-stream urine specimens were collected from apparently healthy Iraqi individuals; hence considered as the control group. All specimens were collected from November 2021 to February 2022. The IL-17 was estimated by enzyme linked immunosorbent assay from urine samples in patients with E. coli and S. aureus as well as control group. The results revealed that IL-17 levels were highly significant at P ˂ 0.05 higher in UTI patients infected with E. coli and S. aureus infections than in controls (670.21 ± 67.7, 506.85 ± 44.8 vs 308.51 ± 9.12 pg/ml respectively). Simultaneously, significant differences in IL-17 levels in patients with E. coli and S. aureus infections were noticed as well. The results also noted a non-significant increase of IL-17 in female patients and control than male group