Uncommon, rapidly progressing, and eventually fatal neurological condition called human prion disease. While most occurrences are sporadic, many can be acquired or inherited. In the current study, we focus on the case of a 63-year-old man who initially had vision problems then exhibits difficulty using his right side for daily activities and who begins to experience frequent falls with gait instability about a week after receiving the second dosage of the novel Pfizer-BioNTech messenger ribonucleic acid (mRNA) COVID-19 vaccination. Confidential findings confirmed the fatal diagnoses of sporadic Creutzfeldt-Jakob disease following a thorough study.
Creutzfeldt-Jakob disease, COVID-19, Pfizer-BioNTech, mRNA, vaccine, prion disease.