Role of IL-33, TSLP, and their receptor in the pathogenicity of asthmatic patients in Basrah province

Abstract

Case /control study were started from March 2021 to January 2022 in Basrah province, Southern Iraq. Eighty-eight cases were divided into two groups 58 (66%) patients and 30 (34%) healthy control individuals their ages ranged between 30 and 60 years old. they were divided by sex into 44 (50%) males and 44 (50%) females. According to the age, the patients and healthy control were divided into three age groups (30–40 years old, 41–50 years old, and 51–60 years old), and their numbers were 29 (33%), 30 (34 %), and 29 (33%), respectively. The results revealed that all markers which used in this study (IL-33, ST2, TSLP and TSLP-R) are elevated significantly in asthmatic patients when compared with healthy control, P. value (0.001, 0.003, 0.001 and 0.001), respectively.