Synthesis and Characterization of Hybrid Polymers for Bone Regeneration based on Polymethacrylate

Abstract

The study was mainly focused on the synthesis and identification of hybrid polymers based on the reversible additions of a series of methyl acrylate monomers, which are iso_Butyl methacrylate and Hydroxypropyl methacrylate using 3-(trimethoxysilyl)propyl methacrylate monomer to form an artificial silica. The produced silica is used in numerous applications that could be transformed into hybrid polymers to restore human bones. Three sections that the study addressed. The copolymers (IBMA-TMS) ، (IBMA-HEMA) were synthesized using benzoylperoxide as an initiator through free radical polymerization. Then, the chemical structures of the polymers were identified using the X-ray analysis to find out the changes that occurred on the polymer’s surface. The FT-IR spectrophotometry was utilized to ensure the skeletal structure of the polymers, which then confirmed that all the obtained bands corresponded to the chemical structure of the polymers. Additionally, difference Thermogravimetry (DTG) was conducted on the polymers to find out their thermal and oxidational stabilities. Likewise, thermogravimetric analysis (TGA) has been used to monitor the percentage of the lost polymers at various temperatures until reaching the max-temperature where the polymers are dissociated at. It was found that the best-synthesized polymer was conducted during the period of (3 hr.) at (70 ℃). The dryness of the polymer was achieved at (40 ℃) for (15 days), and then at (60 ℃) for (10 days) to obtain the solid hybrid polymer.