Abd. Malik Wisdawati Wisdawati Aktsar Roskiana Ahmad


Carthamus tinctorius, extensively applied in curing diseases in many parts of the world, since it is known as fake saffron. Some etnopharmacology approaches relate the antioxidant properties of this plant, polyphenols especially flavonoids, with the antimicrobial and antiviral activities. This review provides a summary of the antioxidant, antimicrobial and antiviral effects of C. tinctorius with the latest reports on developing a new perception of safflower for its antiviral potency. Referring to some data regarding the phytochemical constituents of C. tinctorius which are substantial to give pharmacological effects. For instance, luteolin and its glucopyranosides, and dehydroabietylamine in leaves. Including hydroxysafflor yellow A, carthamin, isolated flavonoid compounds in flower, while seed oil is composed of serotonin derivatives. The interesting compounds are flavonoids, including carthamin, which have significant effects on bacteria, fungi as well as viruses. Hence, C. tinctorius has a promising constituent to be developed as an antiviral agent.

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Carthamus tinctorius, flavonoids, antioxidant, antimicrobial, antiviral

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