Relationship between infant jaundice- children with viral hepatitis and hepatic enzymes levels

Abstract

There are different reasons of jaundice, the most important reasons are the viral infection. current study included a comparison between some important hepatic enzymes of the newborn were suffering from pathological jaundice and young children, with age under fourteen years, who are suffering from the virus hepatitis. The study includes (82) patients suffering from jaundice from both genders which divided into four groups. G1(newborns patients age 1-14 days), G2 (newborns control 1- 14 days), G3 (young children age 1-14 years) G4 (young children age control 1-14 years). All samples were obtained from the children's parlors of the children's hospital in Karbala Province . The present study focus on hepatic enzymes which effected with jaundice. The levels of enzymes activities (ALT, AST, and ALP) in their normal were: (10 ± 2.4IU / L, 9.9 ±1.79 IU/L, 19.6 ± 2.05 K. A. U / 100 ml) for G1 (group one) respectively wasn't different from the control group , which were ( 9.8 ± 1.7 IU / L , 8.4 ± 1.49 IU/L , 19 ± 0.9 K . A. U / 100 ml). Which it be noticed that there is significant rising in the activity of enzymes (ALT , AST , ALP ) in the case of the third group where the average were ( 170 ± 15.9 IU / L , 59.3 ± 7.6 IU/L , 57.5 ± 6.9 K . A. U / 100 ml ) respectively , Comparing with the control group , average activity of these enzymes were ( 7.4 ± 2.0 IU / L , 4.3 ± 1.4 IU/L , 12.3 ± 2.0 K . A. U / 100 ml) .(King Armstrong Unite /100 ml).