Biomedical Evaluation of Biosynthesized Feo:Cuo Ncs by Nigella Sativa Seeds Extract Against Breast Cancer Cell Line, and Bacterial Strains

Abstract

Using an economical, low-cost and safe method, iron oxide nanoparticles and copper oxide nanoparticles were prepared in a very short time using green synthesis technology and Nigella sativa seed extract, which is a reducing and covering agent at the same time. The prepared particles were identified through different techniques, as the results of X-ray diffraction (XRD) confirmed the composition of the two materials, the visible-ultraviolet spectrometer showed the presence of two absorption peaks in the infrared region and in the ultraviolet region, and the shape and size of the particles were determined by transmission electron microscopy. (TEM) It was spherical in shape and size ranged between 5 - 30 nm. The antibacterial activity was studied as well as the activity of the prepared material was also studied in the treatment of human breast cancer line MCF-7, where it was shown that the prepared material is well active to work in anti-cancer applications.