Increased Uric Acid Levels in Patients with Hypertension: The Role of Calcium Channel Blockers and Beta Blockers

Abstract

Background: One of the most common issues that is arising globally is premature cardiovascular death, which is caused by hypertension. With the passage of time, the occurrence of cardiovascular diseases and hypertension is also increasing globally. Currently, the incidence of deaths that are caused by hypertension is about 33% worldwide.Objective: To do a comparison of the effects of calcium channel blockers and beta blockers on increased uric acid levels in people with hypertension.Study design: An analytical cross-sectional studyPlace and Duration: This study was conducted in Sulaiman Roshan Medical College Hospital TandoAdam from May 2022 to May 2023.Methodology: There were a total of 80 people selected to be a part of this research. All of the participants were diagnosed with hypertension. All of these participants were equally divided into 2 groups, 40 patients each. One group included those patients who received Metoprolol as an antihypertensive (Group A), and the other group received Amlodipine as an antihypertensive. The participants in this research were aged from 40 to 50 years. SPSS version 22 was used to analyze the data. A T-test was applied. MS Excel and Word were used to generate tables and graphs. Results: This research was conducted on a total of 80 patients who were equally divided into 2 groups. All of the participants were between 40 and 50 years old. The average age was calculated to be 46 years. The average weight was 73 kg. The average HbA1c level was 5.1%. There were a total of 42 males and 38 females.Conclusion: In conclusion, there was no significant difference between amlodipine and metoprolol on serum uric acid levels in patients with hypertension.