Study of Some Gram-Negative Bacteria from Blood Cultures Among Neonatal Iraqi Patients and their Antibiotics Resistance Pattern
Keywords:
Blood stream infection, Neonatal septicemia, Blood culture, Anti-microbial susceptibility, Bacterial isolates.Abstract
Background and Objective: Neonatal sepsis is a serious condition that can result in death if treatment is delayed. The current study looked at the prevalence of Gram-negative bacteria species that are implicated in bloodstream infection (BSI) among neonates admitted at the Medical city, Baghdad, as well as their antibiotic resistance patterns. Materials and Methods: The BacT/ALERT 3D device (Bio-Merieux, France) was used to culture all the blood samples while the API system was used to identify the pathogenic organisms at the species level. The Kirby-Bauer method was used to determine the antibiotic susceptibility of the identified microbes. The study considered a total of 125 blood cultures collected from newborns who were suspected to be born with bloodstream bacteremia. Results: Among the 23 positive cases with Gram-negative bacteria, the rate was higher in the males [15 (65.2%)] compared to the females [8 (34.7%)]. Klebsiella pneumoniae was found to be the most identified Gram-negative bacteria in the studied blood samples [10 (43.4%)]. Conclusion: Tigecyclin was the most potent antibiotic against the identified Gram-negative bacteria.
