Relation of Enterococcus Faecalis with Wound Infection Post Abdominoplasty and Role of CRP in Infection

Abstract

Enterococcus faecalis is the third most common pathogen to be isolated from surgical site infections and is one of the most common pathogens to be isolated from all types of wounds. In this regard, very little is known about the prevalence of E. faecalis that is isolated from surgical wound infections, as well as their antimicrobial susceptibility and immune status of those patients. This cross-sectional study conducted in Kirkuk city from the period from 1/1/2017 to 1/2/2021. A total of 170 wound swabs were collected from patients of wound infection post abdominoplasty, as well as 30 samples for uninfected persons as control group. Five ml of venous blood was collected from each subject for determination of IL-1 and C-RP level. The study showed that 35.88% of patients with wound post abdominoplasty have pure positive culture and 21.18% mixed culture. all E. faecalis isolates were sensitive to toward carbenicillin and imipenem (100%), 95.2% sensitive to ampicillin, 092.9% sensitive to nitrofurantoin, while all E. faecalis isolates were resistant to nalidixic acid and Clindamycin. The study demonstrated that the highest mean of CRP level was found patients with wound infected by E. faecalis (22.23 mg/dl) comparing with the control group (4.53 mg/dl). The study demonstrated t that the highest mean of IL-beta level was found among wound infected with E. faecalis (33.76 pg/ml) comparing with the control group (8.28 33.76 pg/ml) with highly significant difference.