Study of the Effect of Morgina Oleifera on Chromosome Abnormalities in white Mice

Abstract

The present work was designed to detect the genetic effects of the aqueous extract of Moringa oleifera leaves and to show the effectiveness of this extract in inhibiting the targeted genetic mutations by the carboplatin. Three concentrations of the extract were chosen to study the genetic effects. The body these concentrations were given for 35 days to white mice and based on some genetic tests that included chromosomal aberrations in bone marrow cells and after reaching the best dose, for example, from Moringa oleifera 1500 gm/ kg which is the dose that gave the least number of chromosome deviations, the effect of this dose is studied In protecting the cells of the bone marrow from the side effects of the carboplatin drug, the effect of the drug carboplatin was studied at the same time period and at a dose of 90 mg / kg of body weight.