Synthesis And Characterization of Polyethylene Amine (PEI) Coated with Superparamagnetic Iron Oxide Nanoparticals (Spions) By Using Co-Precipitation Method

Abstract

This study aims to prepare and study the polyethylene amine (SPIONs-PEI) super-magnetic nanoparticles, considering that these nanomaterials are an important class because of their outstanding physical and chemical properties used in various applications such as medical, chemical, and biological applications.The supermagnetic iron oxide nanoparticles Fe3O4 coated with a biopolymer of polyethylene amine SPIONs-PEI was prepared by chemical method, which is the co-precipitation method by preparing Fe+2 and Fe+3 salts in an aqueous solution by precipitating NaOH and sodium citrate salt as a material. On the surface and inside a closed system, using an inert atmosphere for nitrogen gas N2 and in the packaging method, the preparation is ex-situ method, and this method is easy and inexpensive.The nanoparticles were diagnosed using a set of techniques, including X-ray diffraction, VSM analysis, ZP zeta potential, DLS zeta sizer , SEM scanning electron microscope, and transmission electron microscopy TEM analysis.Where the XRD technique showed that the supermagnetic nanoparticles coated with SPIONs-PEI polymer contain the crystal structure and that the polymer coating did not affect its crystal phase and it is within the nanomaterial ranges which is estimated at (~10nm), and the analysis of a sample technique Magnetic Vibration VSM It was found that the unwrapped magnetic nanoparticles coated with SPIONs-PEI polymer possess magnetic properties but it decreases with increasing PEI concentration by 20% which is sufficient to respond to the magnetic field. The results of the Zeta potential also showed that the nanoparticles before encapsulation were negative about (-33.16mV), and the polyethylene amine-coated polymer had a positive charge after coated of (28.49mV). Either the hydrodynamic size of the DLS was about (7.27 nm) for the uncoated particles and (9.85 nm) for the SPIONs-PEI coated particles. The results of SEM scanning electron microscopy diagnosis showed that nanoparticles before and after encapsulation retained spherical geometric shapes with sizes of about (~20 nm), and that the real size of particles before and after encapsulation was within the nanoscale using TEM technique was about (~18 nm).