Evaluation of Some Immunological Aspects and Lipid Profile Among Type I and Type II Diabetes Mellitus in Iraqi Patients of Basrah Province

Abstract

Diabetes mellitus is a long-standing metabolic disorder due to insufficient insulin secretion or no response for insulin result in increased blood glucose level leading to multiple signs and symptoms. One hundred sixty nine participants were enrolled in this study from May 2022 to August 2022. The sample had been taken from patients attended diabetic unit in Basrah city, Iraq. Serum samples were tested to investigate and evaluate the level of lipid profile and anti-GAD 65 by ELISA technique. The levels of all biochemical markers that were found statistically significant differences when compared between type 1 and its control, except HDL. While, the only biochemical markers levels of FBS and HbA1c that were found statistically significant differences when compared between type 2 and its control. Anti-GAD 65 was found to be elevated (11.64±3.59), (12.28±4.42) in patients with T1DM and T2DM respectively when compared with controls group for each patient groups with highly significant differences, the aim of the present study is to compare the role of anti-GAD 65 and the level of lipid profile between patients and control groups.