Comparison Gene Expression of BARCA1 and BARCA2 and complete blood counts in the Blood Serum of Women with Breast Cancer in Ramadi City

Abstract

Breast Cancer is one of cancer types which appear in the breast tissues. The current study aimed to study and evaluate the level of gene expression of the BARCA1 and BARCA2 genes and the concentration levels of these genes in the blood serum of women with breast cancer in Ramadi city, the center of Anbar Province. Then, to compare these variables with companions and healthy people as a control group. In addition, to showing changes in physiological blood characteristics of breast cancer patients and the companion group, and comparing them with healthy as a control group. The results of gene expression between the BARCA1 and BARCA2 genes showed that there were significant differences at the level of probability (P0.05), with an increase in the level of gene expression of the BARCA2 gene by (2.002) in the diseased group compared to the healthy ones, with the presence of significant differences between the two genes compared to the control group, and the high level of expression coincided The gene expression of the BARCA2 gene was associated with a decrease in blood tests in the blood plasma of breast cancer patients. Therefore, the obtained results of the study showed that there is a close relationship between the level of gene expression and the blood biochemical characteristics of breast cancer patients.