Synthesis, Characterization and Study Biological Activity for New (Heterocyclic) Compounds from Chalcone Derivative

Abstract

This research involve synthesis heterocyclic compound by many steps. The first step react 2-amino-6-methoxy benzothiazole with 2,4-dimethoxy acetophenone to get azo compound (1) . The second step involve react (1) with 4-dimethyl amino benzaldehyde to get chalcone compound (2) . the last step is react (2) with hydrazine, phenyl hydrazine , to form pyrazol derivatives (3-4) and react compound (2) with malononitrile and ethylcyano acetate to form pyridine derivatives (5-6) and react compound (2) with thiourea to obtain the thiazine derivative (7). All prepared compounds have been diagnosed by (FT-IR and 1H-NMR ) Spectroscopy and after diagnosis of spectra compound their biological effect was studied on two type anticancer and antioxidant