Background: The most prevalent human pathogen, Staphylococcus sp., is in charge of several chronic and serious diseases especially oral dental diseases. A growing body of research shows that persisters are linked to treatment failure and recurrence of persistent illnesses. While several essential oils were said to have activity as antimicrobial effects on growing Staphylococcus spp., the effects of essential oils on Staphylococcus sp. richer in persisters have not been studied. Methodology: In this investigation, 35 Staphylococcus aureus isolates were obtained from patient infections' oral cavities and were thoroughly characterized and identified using standard bacteriological techniques, biochemical tests, and the VITEK-2 system compact. Evaluation of the antibacterial capabilities of essential oils to the same MDR under research is done using susceptibility tests for various antibiotics on S. aureus MDR. Different essential oil concentrations obtained from sources such as medicinal plants and herbs are employed as antibacterials. Results: When compared to medicines, these essential oils showed antibacterial efficacy against clinical bacterial isolates of MDR S. aureus.
essential oil, antimicrobial, Staphylococcus aureus, MDR