Study of Human Ferritin and C-Reactive Protein in Patients with COVID-19 in Wasit Province, Iraq

Abstract

Serum ferritin is an iron storage protein with a primary role of regulating cellular oxygen metabolism, Ferritin has emerged as a key in the immune system, and its role as an acute phase reactant, recent studies have focused on the role of serum inflammatory markers that predict COVID-19 Damage to the organs, such as the liver and spleen, can also cause ferritin levels to rise. In one study of COVID-19 patients, researchers discovered that those with severe and very severe COVID-19 had higher serum ferritin levels, with serum ferritin levels in the very severe COVID-19 population being slightly higher than those in the severe COVID-19 group. CRP is a liver-produced protein that acts as an early indicator of infection and inflammation. Clinical studies have shown that changes in the levels of certain blood markers are related to the severity and mortality of patients COVID.19 . Serum C-reactive protein (CRP) has been identified as an essential marker that varies dramatically in COVID19 patients with extreme symptoms. A study was conducted to study of levels for each ferritin and CRP in COVID.19 patients and compared it with control group according age and gender. The results showed a highly significant of ferritin levels (P value <0.001) between patients and control and non significant Between male and female within patients (P value 0.6 NS) but a highly significant Between male in control & female in patients and Between female in control & male in patients (P value <0.001). Ferritin rustles according to age showed a highly significant for age <40 (P value <0.001). The rustles of CRP showed a highly significant between patients and control and non significant Between male and female within patients (P value 0.093 NS). CRP rustles according to age showed a highly significant for age <40 (P value <0.001).