Biological Efficacy of Ammi Majus (Apaceae) Extracts on Normal Human Lymphocytes

Abstract

Ammi majus is a medicinal plant that contains bioactive compounds. Some of these active compounds were extracted using 80% ethanol and water by continuous extraction using the Soxhlet. The effective compounds in the extract were detected using qualitative disclosures. The effect of the active compounds of the extracts on the growth of normal human lymphocytes in vitro at five concentrations. 10, 5, 2.5, 1.25, 0.625 mg/ml were studied. The results showed that there were significant differences at the probability in P<0.05 for the extracts, especially the concentrations of 10.5 mg/ml, where the percentage of cell viability for the ethanolic extract was 115.09% and 120.07%, respectively. As for the flavonoid extract, the percentage of cell viability was 106.74% and 157.19%, respectively.